Hydroxycinnamic acid amide derivatives of polyamines reverse spermine-induced CNS excitation
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چکیده
منابع مشابه
Preparation and biological assessment of hydroxycinnamic acid amides of polyamines.
Many plants contain hydroxycinnamic acid conjugates of polyamines that are remarkably similar in general structure to the acylated polyamines found in spider and wasp toxins. In an effort to determine whether these compounds might play a role in the chemical defense of plants against arthropod pests we synthesized a variety of analogues of the coumaric (4-hydroxycinnamic) acid conjugates of di-...
متن کاملCharacterization of hydroxycinnamic acid derivatives binding to bovine serum albumin.
Hydroxycinnamic acid derivatives (HCAs) are a group of naturally occurring polyphenolic compounds which possess various pharmacological activities. In this work, the interactions of bovine serum albumin (BSA) with six HCA derivatives, including chlorogenic acid (CHA), caffeic acid (CFA), m-coumaric acid (m-CA), p-coumaric acid (p-CA), ferulic acid (FA) and sinapic acid (SA) have been investigat...
متن کاملHydroxycinnamic acid amide derivatives, phenolic compounds and antioxidant activities of extracts of pollen samples from Southeast Brazil.
Seven bee pollen samples (C1-C7) with different palynological sources were harvested from Pindamonhangaba municipality (Southeast Brazil). Methanol extracts of untreated samples (control), samples frozen at -18 °C and samples frozen and then dried were analyzed by HPLC/PAD/ESI/MS/MS. Flavonoid diglycosides of quercetin, kaempferol, isorhamnetin and patuletin were detected, together with hydroxy...
متن کاملSynthesis and Antibacterial Activity of Amide Derivatives from Acrylopimaric Acid
This paper reports on the synthesis of a series of amide derivatives from acrylopimaric acid (APA). The derivatives contained aromatic groups and were characterized by IR, HNMR, MS, and elemental analysis. The antibacterial activity of the derivatives against Gram-negative bacteria and Gram-positive bacteria were also investigated. When compared with the other derivatives, compounds 3a and 3f s...
متن کاملStabilization of Protoplasts and Spheroplasts by Spermine and Other Polyamines.
Tabor, Celia W. (National Institute of Arthritis and Metabolic Diseases, Bethesda, Md.). Stabilization of protoplasts and spheroplasts by spermine and other polyamines. J. Bacteriol. 83:1101-1111. 1962.-Spermine (10(-3)m) or spermidine prevents lysis of lysozyme-produced protoplasts of Escherichia coli W, E. coli B, and Micrococcus lysodeikticus in hypotonic media. Spheroplasts prepared by the ...
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ژورنال
عنوان ژورنال: Pharmacology Biochemistry and Behavior
سال: 2015
ISSN: 0091-3057
DOI: 10.1016/j.pbb.2015.03.014